1. Introduction
\nAntimicrobial resistance (AMR) is one of the most serious global public health threats, particularly in hospital settings. Intensive Care Units (ICUs) represent high-risk environments for the emergence and spread of multi-drug resistant (MDR) bacteria due to the frequent use of broad-spectrum antibiotics, invasive procedures, prolonged hospital stays, and critically ill patients with weakened immune systems.
\nMDR bacteria such as Acinetobacter baumannii, Klebsiella pneumoniae, Pseudomonas aeruginosa, Escherichia coli, and Staphylococcus aureus have been increasingly reported worldwide, causing severe infections with limited therapeutic options. In Libya, data on the prevalence and patterns of MDR bacteria in ICUs are limited, highlighting the need for systematic surveillance studies.This study aims to determine the prevalence of MDR bacteria in ICUs at Tripoli Hospitals and provide essential data to support infection control and antibiotic stewardship programs.<\/p>\n
\n2. Research Problem
\nThe lack of updated epidemiological data on MDR bacteria in Libyan ICUs hinders effective infection control strategies and rational antibiotic use. There is an urgent need to evaluate the prevalence and resistance patterns of bacterial pathogens in ICU settings to guide clinical and public health interventions.
\n3. Aim of the Study
\nTo determine the prevalence of multi-drug resistant bacteria in intensive care units at Tripoli University Hospital, Tripoli, Libya.
\n4. Objectives
\n4.1 General Objective
\nTo assess the prevalence and antibiotic resistance patterns of bacterial pathogens isolated from ICU patients.
\n4.2 Specific Objectives
\n1. To isolate and identify bacterial pathogens from clinical specimens of ICU patients and to determine the prevalence of multi-drug resistant bacterial isolates.
\n2. To evaluate the antibiotic susceptibility profiles of the isolated bacteria and to identify the most common MDR bacterial species in ICU settings.
\n3. To assess risk factors associated with MDR infections (e.g., duration of ICU stays, invasive devices, prior antibiotic use).
\n4. To provide recommendations for infection control and antibiotic stewardship.<\/p>\n","protected":false},"parent":0,"template":"","scientific-departments":[10],"class_list":["post-2368","research-projects","type-research-projects","status-publish","has-post-thumbnail","hentry","scientific-departments-department-of-microbiology"],"acf":[],"_links":{"self":[{"href":"https:\/\/lbtrc.edu.ly\/en\/wp-json\/wp\/v2\/research-projects\/2368","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/lbtrc.edu.ly\/en\/wp-json\/wp\/v2\/research-projects"}],"about":[{"href":"https:\/\/lbtrc.edu.ly\/en\/wp-json\/wp\/v2\/types\/research-projects"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/lbtrc.edu.ly\/en\/wp-json\/wp\/v2\/media\/1493"}],"wp:attachment":[{"href":"https:\/\/lbtrc.edu.ly\/en\/wp-json\/wp\/v2\/media?parent=2368"}],"wp:term":[{"taxonomy":"scientific-departments","embeddable":true,"href":"https:\/\/lbtrc.edu.ly\/en\/wp-json\/wp\/v2\/scientific-departments?post=2368"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}