{"id":659,"date":"2025-05-31T19:11:35","date_gmt":"2025-05-31T17:11:35","guid":{"rendered":"https:\/\/lbtrc.edu.ly\/en\/?post_type=research-projects&#038;p=659"},"modified":"2026-02-08T11:02:49","modified_gmt":"2026-02-08T09:02:49","slug":"%d8%a5%d9%86%d8%ac%d8%a7%d8%b2%d8%a7%d8%aa-%d8%ac%d9%8a%d9%86%d9%8a%d8%a9-%d8%ac%d8%af%d9%8a%d8%af%d8%a9-%d9%84%d9%85%d9%83%d8%a7%d9%81%d8%ad%d8%a9-%d8%a7%d9%84%d8%ac%d9%84%d9%88%d9%83%d9%88%d9%85","status":"publish","type":"research-projects","link":"https:\/\/lbtrc.edu.ly\/en\/research-projects\/%d8%a5%d9%86%d8%ac%d8%a7%d8%b2%d8%a7%d8%aa-%d8%ac%d9%8a%d9%86%d9%8a%d8%a9-%d8%ac%d8%af%d9%8a%d8%af%d8%a9-%d9%84%d9%85%d9%83%d8%a7%d9%81%d8%ad%d8%a9-%d8%a7%d9%84%d8%ac%d9%84%d9%88%d9%83%d9%88%d9%85\/","title":{"rendered":"New Genetic Advances in Combating Childhood Glaucoma"},"content":{"rendered":"<p data-start=\"234\" data-end=\"636\">Primary Congenital Glaucoma (PCG) is expected to be relatively common in Libya; however, no genetic screening programs currently exist, and data regarding its prevalence and associated pathogenic mutations remain limited.<br data-start=\"455\" data-end=\"458\" \/>This research aims to investigate variants in the <strong data-start=\"508\" data-end=\"518\">CYP1B1<\/strong> gene\u2014specifically in <strong data-start=\"540\" data-end=\"560\">exons II and III<\/strong>\u2014as essential steps toward understanding the genetic basis of the disease.<\/p>\n<p data-start=\"638\" data-end=\"948\">The ultimate medical goal of the study is to support the development of a genetic screening program that enables early diagnosis and timely treatment of affected children <strong data-start=\"809\" data-end=\"851\">before irreversible vision loss occurs<\/strong>. The study also seeks to explore the correlation between genetic mutations and disease severity.<\/p>\n<h3 data-start=\"950\" data-end=\"974\"><strong data-start=\"954\" data-end=\"974\">Study Objectives<\/strong><\/h3>\n<ol data-start=\"975\" data-end=\"1194\">\n<li data-start=\"975\" data-end=\"1082\">\n<p data-start=\"978\" data-end=\"1082\">Collect demographic data and medical histories of patients diagnosed with Primary Congenital Glaucoma.<\/p>\n<\/li>\n<li data-start=\"1083\" data-end=\"1194\">\n<p data-start=\"1086\" data-end=\"1194\">Identify mutations in exons II and III of the <strong data-start=\"1132\" data-end=\"1142\">CYP1B1<\/strong> gene in affected patients and their family members.<\/p>\n<\/li>\n<\/ol>\n","protected":false},"parent":0,"template":"","scientific-departments":[14],"class_list":["post-659","research-projects","type-research-projects","status-publish","has-post-thumbnail","hentry","scientific-departments-genetic-engineering-department"],"acf":[],"_links":{"self":[{"href":"https:\/\/lbtrc.edu.ly\/en\/wp-json\/wp\/v2\/research-projects\/659","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/lbtrc.edu.ly\/en\/wp-json\/wp\/v2\/research-projects"}],"about":[{"href":"https:\/\/lbtrc.edu.ly\/en\/wp-json\/wp\/v2\/types\/research-projects"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/lbtrc.edu.ly\/en\/wp-json\/wp\/v2\/media\/1493"}],"wp:attachment":[{"href":"https:\/\/lbtrc.edu.ly\/en\/wp-json\/wp\/v2\/media?parent=659"}],"wp:term":[{"taxonomy":"scientific-departments","embeddable":true,"href":"https:\/\/lbtrc.edu.ly\/en\/wp-json\/wp\/v2\/scientific-departments?post=659"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}